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For US patients
EVERY
WOMAN HAS THE
TO CHOOSE HER PATH FORWARD
Actual breast reconstruction patient with Natrelle INSPIRA® Breast Implants.
Individual results may vary.
Supporting
women and their breast
cancer journeys
If you’ve decided to have reconstruction with breast implants, Natrelle® has a wide range of innovative offerings designed to meet your expectations.
LISA
“Reconstruction after breast cancer is a journey. It helped me discover my new normal. It was my choice and
IT’S EXACTLY WHAT I WANTED.”
Actual breast cancer and breast
reconstruction patient with
Natrelle INSPIRA® Breast Implants.
Individual results may vary.
KAYLA
“After testing positive for BRCA2, I decided to have a double mastectomy and reconstruction with implants. Breast reconstruction helped me
MOVE FORWARD.”
Actual breast reconstruction patient with
Natrelle INSPIRA® Breast Implants.
Individual results may vary.
Your GUIDE to surgery
Breast reconstruction basics
When you have a mastectomy, you lose breast tissue, some skin, and possibly your nipple and areola. Breast reconstruction results have improved over the years. While your plastic surgeon can’t give you the same breast you had prior to your mastectomy, he or she may be able to give you a reasonable likeness of your premastectomy breast.
Immediate or delayed reconstructive surgery
Will you begin your reconstruction surgery immediately—at the time of your mastectomy—or will you delay your reconstruction surgery until after you have healed?
Advantages
Disadvantages
Advantages
Immediate reconstruction
Eliminates an operation since it’s performed at the same time as the mastectomy.
Delayed reconstruction
Provides time to treat and evaluate the cancer. Some women may need radiation after mastectomy, which can cause problems like delayed healing and scarring.

Provides time to quit smoking and/or lose or gain weight. Smoking, being overweight or too thin can cause problems with your reconstruction.
Disadvantages
Immediate reconstruction
Requires a longer surgery.
Delayed reconstruction
Requires an additional operation.

Creates a time where you will have the appearance of no breast(s).
Your surgeon will determine if you are an appropriate candidate for immediate reconstruction or if it would be better for you to have a delayed procedure.
I’M
TRUSTING MY
journey
Actual breast cancer and breast reconstruction patient with Natrelle INSPIRA® Breast Implants.
Individual results may vary.
I’M
TRUSTING MY
journey
Implant-based breast reconstruction
This type of reconstruction shapes the breast with implants and is usually performed in 2 stages: Using a tissue expander in the first stage and then inserting a breast implant under the muscle in the second stage.

An innovative advancement allows for placement of a tissue expander or silicone breast implant over the chest muscle (prepectorally). Learn more about prepectoral reconstruction below, and talk to your surgeon to determine whether this approach is an option for you.
Advantages of Implant-based Reconstruction
The procedure is performed in areas where you are already having surgery; no new incisions are usually required.
Disadvantages of Implant-based Reconstruction
Implants are not lifetime devices and you may require additional surgery in the future.
i am
what i choose
Actual breast cancer and breast reconstruction patient with Natrelle INSPIRA® Breast Implants.
Individual results may vary.
Over the muscle (pre-pec) technique
This technique allows for placement of a tissue expander or silicone-filled breast implant over the chest muscle (prepectorally).
Advantages of Pre-pec Technique
Because the chest muscle isn’t cut:
  • Potentially shorter recovery time
  • Potentially less pain or side effects caused by cutting the chest muscle
Because the implant is placed over the muscle:
  • Surgeon has greater control of shape and form of the breast
  • Flexing your chest muscle may/should not make the breast implants move in unpleasant, unnatural ways
Disadvantages of Pre-pec Technique
  • Not all patients are candidates for pre-pec placement because it requires enough tissue in good condition after a mastectomy
  • Risk of visible rippling of the implant
  • Not all surgeons have experience with this newer technique
Subpectoral (under the muscle) technique
This technique involves placing a breast implant under the chest muscle. In some cases, this can be done immediately after the mastectomy.

If you have minimal breast tissue, your surgeon may recommend placing a tissue expander under your skin and chest muscle before placing the implant. A tissue expander is like a balloon, which can be inflated to stretch the skin and muscle over several months, making room for your implant.
Advantages of Sub-pec Technique
  • Many surgeons have experience with this well-known technique
  • May minimize risk of visible rippling of the implant
Disadvantages of Sub-pec Technique
Because the chest muscle is cut:
  • Potentially longer recovery time
  • Potentially more pain or side effects caused by cutting the chest muscle
Because the implant is placed under the muscle:
  • Flexing your chest muscle may make the breast implants move in unpleasant, unnatural ways
Two-stage vs one-stage breast reconstruction
Two-stage breast reconstruction is the most common type of breast reconstruction performed. The first stage involves placing a tissue expander to recreate a breast pocket after the breast tissue has been removed. In the second stage, the implant is placed into the breast pocket.

One-stage, or direct-to-implant (DTI), breast reconstruction involves placing the implant immediately after breast tissue has been removed.
Advantages of
DTI Reconstruction
The breast implant can be placed immediately instead of requiring an additional tissue expander step.
Disadvantages of
DTI Reconstruction
Not every patient is a candidate.
First stage
This procedure first uses a tissue expander, which is surgically inserted and slowly expanded over time to create a space for the implant. Typically, you will meet with your plastic surgeon every other week to fill the expander with sterile saline in order to gradually stretch the skin.
The tissue expander with over 30 years of clinical experience
Natrelle® 133S Smooth Tissue Expanders are made to match Natrelle INSPIRA® Round Gel Breast Implants. This means that the tissue expander creates a space customized for the breast implant.
Second stage
Once the space reaches the correct size and the tissue has healed, a second surgery will remove the tissue expander and replace it with the breast implant. If a mastectomy was only performed on one breast, some patients choose to have the other breast augmented to maintain symmetry.
The #1 surgeon-selected gummy breast implant collection in the US*
Natrelle INSPIRA® Round Gel Breast Implants are designed to give you the look and feel that’s important to you.
*Based on surgeon survey data, July 2019 (N = 80).
Your choice. Your look.
before
After
before
After
Primary reconstruction with
Natrelle INSPIRA® Cohesive Style SCF-560
Photos provided by Dr Mark L. Venturi. Individual results may vary.
See more results
ALLERGAN,
the maker of Natrelle®, has been at the forefront of breast reconstruction advancements.
learn more
Natrelle® Breast Implants Important Information
SEE MORE +
Natrelle® Breast Implants Important Information
Who may get breast implants?
 Natrelle® Breast Implants are approved for women for the following:
IMPORTANT SAFETY INFORMATION
Who should NOT get breast implants?
What should I know before getting breast implants?
What should I tell my doctor?
Tell your doctor if you have any of the following conditions, as the risks of breast implant surgery may be higher:
What are some complications with breast implants?
Key complications are reoperation, implant removal with or without replacement, implant rupture with silicone-filled implants, implant deflation with saline-filled implants, and severe capsular contracture (severe scar tissue around the implant). Other complications include asymmetry, nipple/breast/skin sensation changes, scarring, or wrinkling/rippling. Talk to your doctor about other complications.
What is BIA-ALCL?
 Breast Implant–Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) is a type of non-Hodgkin’s lymphoma (cancer of the immune system). While uncommon, BIA-ALCL has been associated with silicone and saline breast implants. In most cases, BIA-ALCL is found in the scar tissue and fluid near the implant, but in some cases, it can spread throughout the body. In most cases it is treated successfully with surgery to remove the implant and surrounding scar tissue, and in some patients, also treatment with chemotherapy and radiation therapy. BIA-ALCL is most commonly associated with textured implants. If you are experiencing symptoms of persistent swelling, the presence of a mass, or pain in the area of an implant months or years after your implant surgery, please contact your healthcare provider.
Talk to your doctor. For more information see the patient brochures at www.allergan.com/products. To report a problem with Natrelle® Breast Implants, please call Allergan at 1-800-433-8871.
Natrelle® Breast Implants are available by prescription only.
Natrelle® 133S Smooth Tissue Expanders Important Information
Approved Uses
 Natrelle® 133S Smooth Tissue Expanders are approved for breast reconstruction following mastectomy, treatment of underdeveloped breasts, and treatment of soft tissue deformities.
IMPORTANT SAFETY INFORMATION
Who should NOT get tissue expanders?
Do not use if you:
What else should I consider?
What are possible complications?
Deflation, tissue damage and/or appearance of the implant through the skin, infection, unwanted shape, unintended blood or fluid collection, capsular contracture (tightening of scar tissue that causes the breast to harden), premature device removal, bone/pain/sensation changes, and inflammation.
For more information, please visit www.allergan.com/products. To report a problem with Natrelle®, please call Allergan at 1-800-433-8871.
Natrelle® 133S Smooth Tissue Expanders are available by prescription only.
Approved Uses
BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow’s feet lines, and frown lines between the eyebrows in adults.
IMPORTANT SAFETY INFORMATION
 BOTOX® Cosmetic may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic:
BOTOX® Cosmetic dosing units are not the same as, or comparable to, any other botulinum toxin product.
There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow’s feet lines, and/or forehead lines.
BOTOX® Cosmetic may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of taking BOTOX® Cosmetic. If this happens, do not drive a car, operate machinery, or do other dangerous activities.
Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.
Do not receive BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.
Tell your doctor about all your muscle or nerve conditions, such as ALS or Lou Gehrig’s disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX® Cosmetic.
Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; have trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to (it is not known if BOTOX® Cosmetic passes into breast milk).
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.
Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.
Other side effects of BOTOX® Cosmetic include: dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids and eyebrows, swelling of your eyelids and dry eyes.
For more information refer to the Medication Guide or talk with your doctor.
To report a side effect, please call Allergan at 1-800-678-1605.

Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide.
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Natrelle® Breast Implants Important Information
SEE MORE +
Natrelle® Breast Implants Important Information
Who may get breast implants?
 Natrelle® Breast Implants are approved for women for the following:
IMPORTANT SAFETY INFORMATION
Who should NOT get breast implants?
What should I know before getting breast implants?
What should I tell my doctor?
Tell your doctor if you have any of the following conditions, as the risks of breast implant surgery may be higher:
What are some complications with breast implants?
Key complications are reoperation, implant removal with or without replacement, implant rupture with silicone-filled implants, implant deflation with saline-filled implants, and severe capsular contracture (severe scar tissue around the implant). Other complications include asymmetry, nipple/breast/skin sensation changes, scarring, or wrinkling/rippling. Talk to your doctor about other complications.
What is BIA-ALCL?
 Breast Implant–Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) is a type of non-Hodgkin’s lymphoma (cancer of the immune system). While uncommon, BIA-ALCL has been associated with silicone and saline breast implants. In most cases, BIA-ALCL is found in the scar tissue and fluid near the implant, but in some cases, it can spread throughout the body. In most cases it is treated successfully with surgery to remove the implant and surrounding scar tissue, and in some patients, also treatment with chemotherapy and radiation therapy. BIA-ALCL is most commonly associated with textured implants. If you are experiencing symptoms of persistent swelling, the presence of a mass, or pain in the area of an implant months or years after your implant surgery, please contact your healthcare provider.
Talk to your doctor. For more information see the patient brochures at www.allergan.com/products. To report a problem with Natrelle® Breast Implants, please call Allergan at 1-800-433-8871.
Natrelle® Breast Implants are available by prescription only.
Natrelle® 133S Smooth Tissue Expanders Important Information
Approved Uses
 Natrelle® 133S Smooth Tissue Expanders are approved for breast reconstruction following mastectomy, treatment of underdeveloped breasts, and treatment of soft tissue deformities.
IMPORTANT SAFETY INFORMATION
Who should NOT get tissue expanders?
Do not use if you:
What else should I consider?
What are possible complications?
Deflation, tissue damage and/or appearance of the implant through the skin, infection, unwanted shape, unintended blood or fluid collection, capsular contracture (tightening of scar tissue that causes the breast to harden), premature device removal, bone/pain/sensation changes, and inflammation.
For more information, please visit www.allergan.com/products. To report a problem with Natrelle®, please call Allergan at 1-800-433-8871.
Natrelle® 133S Smooth Tissue Expanders are available by prescription only.
Approved Uses
BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow’s feet lines, and frown lines between the eyebrows in adults.
IMPORTANT SAFETY INFORMATION
 BOTOX® Cosmetic may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic:
BOTOX® Cosmetic dosing units are not the same as, or comparable to, any other botulinum toxin product.
There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow’s feet lines, and/or forehead lines.
BOTOX® Cosmetic may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of taking BOTOX® Cosmetic. If this happens, do not drive a car, operate machinery, or do other dangerous activities.
Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.
Do not receive BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.
Tell your doctor about all your muscle or nerve conditions, such as ALS or Lou Gehrig’s disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX® Cosmetic.
Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; have trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to (it is not known if BOTOX® Cosmetic passes into breast milk).
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.
Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.
Other side effects of BOTOX® Cosmetic include: dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids and eyebrows, swelling of your eyelids and dry eyes.
For more information refer to the Medication Guide or talk with your doctor.
To report a side effect, please call Allergan at 1-800-678-1605.

Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide.
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